Inwardly Permeating Na Ions Generate the Voltage Dependence of Resurgent Na Current in Cerebellar Purkinje Neurons

Voltage-gated Na channels of cerebellar Purkinje neurons express an endogenous open-channel blocking protein. This blocker binds channels at positive potentials and unbinds at negative potentials, generating a resurgent Na current and permitting rapid firing. The macroscopic voltage dependence of re...

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Autors principals: Aman, Teresa K., Raman, Indira M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865843/
https://ncbi.nlm.nih.gov/pubmed/20410115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0376-10.2010
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