Inwardly Permeating Na Ions Generate the Voltage Dependence of Resurgent Na Current in Cerebellar Purkinje Neurons

Voltage-gated Na channels of cerebellar Purkinje neurons express an endogenous open-channel blocking protein. This blocker binds channels at positive potentials and unbinds at negative potentials, generating a resurgent Na current and permitting rapid firing. The macroscopic voltage dependence of re...

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Main Authors: Aman, Teresa K., Raman, Indira M.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2010
主題:
Brief Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865843/
https://ncbi.nlm.nih.gov/pubmed/20410115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0376-10.2010
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