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Cross-Species Conservation of Open-Channel Block by Na Channel β4 Peptides Reveals Structural Features Required for Resurgent Na Current

Voltage-gated Na channels in many neurons, including several in the cerebellum and brainstem, are specialized to allow rapid firing of action potentials. Repetitive firing is facilitated by resurgent Na current, which flows upon repolarization as Na channels recover through open states from block by...

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Detalhes bibliográficos
Main Authors: Lewis, Amanda H., Raman, Indira M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178407/
https://ncbi.nlm.nih.gov/pubmed/21832183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1428-11.2011
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