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Antagonism of Lidocaine Inhibition by Open-Channel Blockers That Generate Resurgent Na Current

Na channels that generate resurgent current express an intracellular endogenous open-channel blocking protein, whose rapid binding upon depolarization and unbinding upon repolarization minimizes fast and slow inactivation. Na channels also bind exogenous compounds, such as lidocaine, which functiona...

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Bibliografske podrobnosti
Main Authors: Bant, Jason S., Aman, Teresa K., Raman, Indira M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643213/
https://ncbi.nlm.nih.gov/pubmed/23486968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3026-12.2013
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