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Direct Synthesis of Fluorinated Heteroarylether Bioisosteres
[Image: see text] This work delineates a method for the modular synthesis of reagents that are capable of direct incorporation of difluoroalkyl groups onto heterocycles. The scope and generality of this method is exemplified with the difluoroethyl group (along with the introduction of a new reagent...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643141/ https://ncbi.nlm.nih.gov/pubmed/23460402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201300763 |
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