Wird geladen...

Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

[Image: see text] This work delineates a method for the modular synthesis of reagents that are capable of direct incorporation of difluoroalkyl groups onto heterocycles. The scope and generality of this method is exemplified with the difluoroethyl group (along with the introduction of a new reagent...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhou, Qianghui, Ruffoni, Alessandro, Gianatassio, Ryan, Fujiwara, Yuta, Sella, Eran, Shabat, Doron, Baran, Phil S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643141/
https://ncbi.nlm.nih.gov/pubmed/23460402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201300763
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!