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Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

[Image: see text] This work delineates a method for the modular synthesis of reagents that are capable of direct incorporation of difluoroalkyl groups onto heterocycles. The scope and generality of this method is exemplified with the difluoroethyl group (along with the introduction of a new reagent...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhou, Qianghui, Ruffoni, Alessandro, Gianatassio, Ryan, Fujiwara, Yuta, Sella, Eran, Shabat, Doron, Baran, Phil S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643141/
https://ncbi.nlm.nih.gov/pubmed/23460402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201300763
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