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The Development of Selected Reaction Monitoring Methods for Targeted Proteomics via Empirical Refinement

Software advancements in the last several years have had a significant impact on proteomics from method development to data analysis. Herein we detail a method, which uses our in-house developed software tool termed Skyline, for empirical refinement of candidate peptides from targeted proteins. The...

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Autori principali: Bereman, Michael S., MacLean, Brendan, Tomazela, Daniela M., Liebler, Daniel C., MacCoss, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643124/
https://ncbi.nlm.nih.gov/pubmed/22577014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201200042
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