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Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism

Cytochrome P450 (CYP) 1A1 is an extrahepatic monooxygenase involved in the metabolism of endogenous substrates and drugs, as well as the activation of certain toxins and environmental pollutants. CYP1A1 is particularly well known for its ability to biotransform polycyclic aromatic hydrocarbons, such...

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Detalhes bibliográficos
Main Authors: Walsh, Agnes A., Szklarz, Grazyna D., Scott, Emily E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642336/
https://ncbi.nlm.nih.gov/pubmed/23508959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452953
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