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Residues of the 39-Loop Restrict the Plasma Inhibitor Specificity of Factor IXa

The two plasma inhibitors, protein Z-dependent protease inhibitor (ZPI) and tissue factor pathway inhibitor (TFPI), effectively inhibit the activity of activated factor X (FXa); however, neither inhibitor exhibits any reactivity with the homologous protease activated factor IX (FIXa). In this study,...

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Autori principali: Yang, Likui, Rezaie, Alireza R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642315/
https://ncbi.nlm.nih.gov/pubmed/23530052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.459347
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