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Contribution of the NH2-terminal EGF-domain of Factor IXa to the Specificity of Intrinsic Tenase

Factor IXa (FIXa) is a vitamin K-dependent coagulation serine protease which binds to factor VIIIa (FVIIIa) on negatively charged phospholipid vesicles (PCPS) to catalyze the activation of factor X (FX) to factor Xa (FXa) in the intrinsic pathway. Fluorescence resonance energy transfer (FRET) studie...

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Detalhes bibliográficos
Main Authors: Qureshi, Shabir H., Yang, Likui, Rezaie, Alireza R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511649/
https://ncbi.nlm.nih.gov/pubmed/23014580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-06-0436
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