Methionine Adenosyltransferase 2B-GIT1 Interplay Activates MEK1-ERK1/2 to Induce Growth in Human Liver and Colon Cancer

Methionine adenosyltransferase 2B (MAT2B) encodes for two variant proteins V1 and V2 that promote cell growth. Using in-solution proteomics, GIT1 (G-protein-coupled receptor kinase-interacting protein 1) was identified as a potential interacting partner of MAT2B. Here we examined the functional sign...

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Main Authors: Peng, Hui, Dara, Lily, Li, Tony W.H., Zheng, Yuhua, Yang, Heping, Tomasi, Lauda Maria, Tomasi, Ivan, Giordano, Pasquale, Mato, Jose M., Lu, Shelly C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642222/
https://ncbi.nlm.nih.gov/pubmed/23325601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26258
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