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A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

A-type lamins encoded by LMNA form a structural fibrillar meshwork within the mammalian nucleus. How this nuclear organization may influence the execution of biological processes involving DNA transactions remains unclear. Here, we characterize changes in the dynamics and biochemical interactions of...

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Hlavní autoři: Mahen, Robert, Hattori, Hiroyoshi, Lee, Miyoung, Sharma, Pooja, Jeyasekharan, Anand D., Venkitaraman, Ashok R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642183/
https://ncbi.nlm.nih.gov/pubmed/23658700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061893
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