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Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours
BACKGROUND: The RNase III enzyme DICER1 plays a central role in maturation of microRNAs. Identification of neoplasia-associated germ-line and somatic mutations in DICER1 indicates that mis-expression of miRNAs in cancer may result from defects in their processing. As part of a recent study of DICER1...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642033/ https://ncbi.nlm.nih.gov/pubmed/23547758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-127 |
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