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Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides
DICER1 is an endoribonuclease responsible for the production of mature microRNAs which are small, single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to mRNA and repressing the expression of target genes. Germ-line mutations in DICER1 are responsible for a r...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953921/ https://ncbi.nlm.nih.gov/pubmed/24065110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.215 |
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