Deletion of IgG-switched Autoreactive B Cells and Defects in Fas(lpr) Lupus Mice

During a T cell-dependent antibody (Ab) response, B cells undergo Ab class-switching and variable region hypermutation, with the latter process potentially rendering previously innocuous B cells autoreactive. Class switching and hypermutation are temporally and anatomically linked with both processe...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Aït-Azzouzene, Djemel, Kono, Dwight H., Gonzalez-Quintial, Rosana, McHeyzer-Williams, Louise J., Lim, Min, Wickramarachchi, Dilki, Gerdes, Tobias, Gavin, Amanda L., Skog, Patrick, McHeyzer-Williams, Michael G., Nemazee, David, Theofilopoulos, Argyrios N.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641794/
https://ncbi.nlm.nih.gov/pubmed/20554953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000698
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki