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Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.

Background genes determine the incidence and severity of lymphoaccumulation and histopathologic manifestations of systemic autoimmunity in mice homozygous for the apoptosis-defective Faslpr mutation. By interval mapping of 274 F2 mice intercrossed between MRL-Faslpr (severe disease) and C57BL/6-Fasl...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Vidal, S, Kono, D H, Theofilopoulos, A N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508615/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9449705/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1817
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