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Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death
Sustained activation of neuronal N-methly D-aspartate (NMDA)-type glutamate receptors leads to excitotoxic cell death in stroke, trauma, and neurodegenerative disorders. Excitotoxic neuronal death results in part from superoxide produced by neuronal NADPH oxidase (NOX2), but how NMDA receptors are c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641334/ https://ncbi.nlm.nih.gov/pubmed/23559014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.111 |
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