Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.

Heparin is required for the binding of basic fibroblast growth factor (bFGF) to high-affinity receptors on cells deficient in cell surface heparan sulfate proteoglycan. So that this heparin requirement could be evaluated in the absence of other cell surface molecules, we designed a simple assay base...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Ornitz, D M, Yayon, A, Flanagan, J G, Svahn, C M, Levi, E, Leder, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1309590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.1.240-247.1992
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