A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.

Cells expressing mutant epidermal growth factor (EGF) receptors have been used to study mechanisms through which EGF increases phospholipase C (PLC) activity. C-terminal truncation mutant EGF receptors are markedly impaired in their ability to increase inositol phosphate formation compared with wild...

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Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Vega, Q C, Cochet, C, Filhol, O, Chang, C P, Rhee, S G, Gill, G N
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 1992
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.1.128-135.1992
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