Selectivity of phospholipase C phosphorylation by the epidermal growth factor receptor, the insulin receptor, and their cytoplasmic domains.

Phosphatidylinositol-specific phospholipase C isozyme gamma (PLC-gamma, Mr 145,000) is an excellent substrate for the epidermal growth factor (EGF) receptor both in vivo and in vitro. PLC-beta-1, another PLC isozyme, is a poor substrate for the EGF receptor. We examined the relative phosphorylation...

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Main Authors: Nishibe, S, Wahl, M I, Wedegaertner, P B, Kim, J W, Rhee, S G, Carpenter, G, Kim, J J
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC53276/
https://ncbi.nlm.nih.gov/pubmed/2153302
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