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Alzheimer’s Disease Drug Discovery: In-vivo screening using C. elegans as a model for β-amyloid peptide-induced toxicity
Alzheimer’s disease (AD) is a complex human neurodegenerative disease. Currently the therapeutics for AD only treat the symptoms. While numbers of excellent studies have used mammalian models to discover new compounds, the time and effort involved with screening large numbers of candidates is prohib...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640579/ https://ncbi.nlm.nih.gov/pubmed/24050239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2012.02.002 |
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