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Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

Accumulation of the β-amyloid peptide (Aβ) is generally believed to be central to the induction of Alzheimer's disease, but the relevant mechanism(s) of toxicity are still unclear. Aβ is also deposited intramuscularly in Inclusion Body Myositis, a severe human myopathy. The intensely studied ne...

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Autori principali: Dostal, Vishantie, Link, Christopher D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185644/
https://ncbi.nlm.nih.gov/pubmed/20972410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2252
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