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Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

Accumulation of the β-amyloid peptide (Aβ) is generally believed to be central to the induction of Alzheimer's disease, but the relevant mechanism(s) of toxicity are still unclear. Aβ is also deposited intramuscularly in Inclusion Body Myositis, a severe human myopathy. The intensely studied ne...

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Detalhes bibliográficos
Main Authors: Dostal, Vishantie, Link, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185644/
https://ncbi.nlm.nih.gov/pubmed/20972410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2252
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