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Functional Analysis of Non-synonymous Single Nucleotide Polymorphisms of Multidrug Resistance Protein 2 (MRP2; ABCC2)
Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide and sulfate conjugates of endo- and xenobiotics. Single nucleotide polymorphisms (SNPs) of MRP2 contribute to interindividual variability in drug disposition and ultimately in drug resp...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640355/ https://ncbi.nlm.nih.gov/pubmed/21691255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328348c786 |
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