Functional Analysis of Non-synonymous Single Nucleotide Polymorphisms of Multidrug Resistance Protein 2 (MRP2; ABCC2)

Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide and sulfate conjugates of endo- and xenobiotics. Single nucleotide polymorphisms (SNPs) of MRP2 contribute to interindividual variability in drug disposition and ultimately in drug resp...

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Bibliographic Details
Main Authors: Megaraj, Vandana, Zhao, Tianyong, Paumi, Christian M, Gerk, Phillip M., Kim, Richard, Vore, Mary
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640355/
https://ncbi.nlm.nih.gov/pubmed/21691255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328348c786
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