Nalaganje...

Blocking HIV-1 entry by a gp120 surface binding inhibitor

We report the mode of action of a proteomimetic compound that binds to the exterior surface of gp120 and blocks HIV-1 entry into cells. Using a one cycle time-of-addition study and antibody competition binding studies, we have determined that the compound blocks HIV-1 entry through modulation of key...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Tsou, Lun K., Chen, Chin-Ho, Dutschman, Ginger E., Cheng, Yung-Chi, Hamilton, Andrew D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640310/
https://ncbi.nlm.nih.gov/pubmed/22487177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.02.079
Oznake: Označite
Brez oznak, prvi označite!