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Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold

A potential anti-HIV and HCV drug candidate is highly desirable as coinfection has become a worldwide public health challenge. A potent compound based on a tetrabutoxy-calix[4]arene scaffold that possesses dual inhibition for both HIV and is described. Structural activity relationship studies demons...

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Detalhes bibliográficos
Main Authors: Tsou, Lun K., Dutschman, Ginger E., Gullen, Elizabeth A., Telpoukhovskaia, Maria, Cheng, Yung-Chi, Hamilton, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849157/
https://ncbi.nlm.nih.gov/pubmed/20202840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.02.043
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