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Synthesis and Anti-Acetylcholinesterase Properties of Novel β- and γ-Substituted Alkoxy Organophosphonates
Activated organophosphate (OP) insecticides and chemical agents inhibit acetylcholinesterase (AChE) to form OP-AChE adducts. Whereas the structure of the OP correlates with the rate of inhibition, the structure of the OP-AChE adduct influences the rate at which post-inhibitory reactivation or aging...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640285/ https://ncbi.nlm.nih.gov/pubmed/23453838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.010 |
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