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Synthesis and Anti-Acetylcholinesterase Properties of Novel β- and γ-Substituted Alkoxy Organophosphonates

Activated organophosphate (OP) insecticides and chemical agents inhibit acetylcholinesterase (AChE) to form OP-AChE adducts. Whereas the structure of the OP correlates with the rate of inhibition, the structure of the OP-AChE adduct influences the rate at which post-inhibitory reactivation or aging...

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Sonraí Bibleagrafaíochta
Main Authors: Ahmed, S. Kaleem, Belabassi, Yamina, Sankaranarayanan, Lakshmi, Chao, Chih-Kai, Gerdes, John M., Thompson, Charles M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640285/
https://ncbi.nlm.nih.gov/pubmed/23453838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.010
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