A Novel Fluorine-18 β-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase

[Image: see text] Radiosynthesis of a fluorine-18 labeled organophosphate (OP) inhibitor of acetylcholinesterase (AChE) and subsequent positron emission tomography (PET) imaging using the tracer in the rat central nervous system are reported. The tracer structure, which contains a novel β-fluoroetho...

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Autors principals: James, Shelly L., Ahmed, S. Kaleem, Murphy, Stephanie, Braden, Michael R., Belabassi, Yamina, VanBrocklin, Henry F., Thompson, Charles M., Gerdes, John M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102964/
https://ncbi.nlm.nih.gov/pubmed/24716794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500024c
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