Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination

Endosomal protein trafficking is an essential cellular process that is deregulated in several diseases and targeted by pathogens. Here, we describe a novel role for ubiquitination in this process. We find that the novel E3 RING ubiquitin ligase, MAGE-L2-TRIM27, localizes to endosomes through interac...

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Détails bibliographiques
Auteurs principaux: Hao, Yi-Heng, Doyle, Jennifer M., Ramanathan, Saumya, Gomez, Timothy S., Jia, Da, Xu, Ming, Chen, Zhijian J., Billadeau, Daniel D., Rosen, Michael K., Potts, Patrick Ryan
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640276/
https://ncbi.nlm.nih.gov/pubmed/23452853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.051
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