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WASH Knockout T Cells Demonstrate Defective Receptor Trafficking, Proliferation, and Effector Function
WASH is an Arp2/3 activator of the Wiskott-Aldrich syndrome protein superfamily that functions during endosomal trafficking processes in collaboration with the retromer and sorting nexins, but its in vivo function has not been examined. To elucidate the physiological role of WASH in T cells, we gene...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623087/ https://ncbi.nlm.nih.gov/pubmed/23275443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01288-12 |
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