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Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks
The Arp2/3-activator Wiskott–Aldrich syndrome protein and Scar homologue (WASH) is suggested to regulate actin-dependent membrane scission during endosomal sorting, but its cellular roles have not been fully elucidated. To investigate WASH function, we generated tamoxifen-inducible WASH-knockout mou...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418315/ https://ncbi.nlm.nih.gov/pubmed/22718907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0101 |
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