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Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

Sorting of cargoes in endosomes occurs through their selective enrichment into sorting platforms, where transport intermediates are generated. The WASH complex, which directly binds to lipids, activates the Arp2/3 complex and hence actin polymerization onto such sorting platforms. Here, we analyzed...

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Autors principals: Derivery, Emmanuel, Helfer, Emmanuèle, Henriot, Véronique, Gautreau, Alexis
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380866/
https://ncbi.nlm.nih.gov/pubmed/22737254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039774
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