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In Vitro Polymerization of F-actin on Early Endosomes

Many early endosome functions, particularly cargo protein sorting and membrane deformation, depend on patches of short F-actin filaments nucleated onto the endosomal membrane. We have established a microscopy-based in vitro assay that reconstitutes the nucleation and polymerization of F-actin on ear...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Muriel, Olivia, Scott, Cameron Christopher, Larios, Jorge, Mercier, Vicent, Gruenberg, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614372/
https://ncbi.nlm.nih.gov/pubmed/28872124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55829
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