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Assembly and Activity of the WASH Molecular Machine: Distinctive Features at the Crossroads of the Actin and Microtubule Cytoskeletons

The Arp2/3 complex generates branched actin networks at different locations of the cell. The WASH and WAVE Nucleation Promoting Factors (NPFs) activate the Arp2/3 complex at the surface of endosomes or at the cell cortex, respectively. In this review, we will discuss how these two NPFs are controlle...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Fokin, Artem I., Gautreau, Alexis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047104/
https://ncbi.nlm.nih.gov/pubmed/33869225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.658865
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