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Human RNA methyltransferase BCDIN3D regulates microRNA processing

MicroRNAs regulate key biological processes and their aberrant expression may lead to cancer. The primary transcript of canonical miRNAs is sequentially cleaved by the RNase III enzymes, Drosha and Dicer, which generate 5′mono-phosphate ends that are important for subsequent miRNA functions. In part...

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書誌詳細
主要な著者: Xhemalce, Blerta, Robson, Samuel C, Kouzarides, Tony
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640255/
https://ncbi.nlm.nih.gov/pubmed/23063121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.041
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