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A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly
Chromodomain proteins (Chp1/Chp2/Swi6/Clr4) bind to methylated H3K9 (H3K9me) and regulate pericentric heterochromatin in fission yeast. Chp1 and Clr4 (H3K9-HMT), bind transcriptionally active heterochromatin, whereas Chp2/Swi6 (HP1 homologs) are recruited during the inactive state. We show that H3K4...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849121/ https://ncbi.nlm.nih.gov/pubmed/20299449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1881710 |
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