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Human RNA methyltransferase BCDIN3D regulates microRNA processing
MicroRNAs regulate key biological processes and their aberrant expression may lead to cancer. The primary transcript of canonical miRNAs is sequentially cleaved by the RNase III enzymes, Drosha and Dicer, which generate 5′mono-phosphate ends that are important for subsequent miRNA functions. In part...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640255/ https://ncbi.nlm.nih.gov/pubmed/23063121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.041 |
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