Inhibition of p38MAPK and CD137 signaling reduce dengue virus-induced TNF-α secretion and apoptosis

BACKGROUND: Hepatic injury in dengue virus (DENV) infection is authenticated by hepatomegaly and an upsurge in transaminase levels. DENV replicates in hepatocytes and causes hepatocyte apoptosis both in vitro and in vivo. Understanding the molecular mechanisms of DENV-induced hepatic injury could fa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nagila, Amar, Netsawang, Janjuree, Suttitheptumrong, Aroonroong, Morchang, Atthapan, Khunchai, Sasiprapa, Srisawat, Chatchawan, Puttikhunt, Chunya, Noisakran, Sansanee, Yenchitsomanus, Pa-thai, Limjindaporn, Thawornchai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Short Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639879/
https://ncbi.nlm.nih.gov/pubmed/23557259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-105
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