RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines

Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morchang, Atthapan, Lee, Regina Ching Hua, Yenchitsomanus, Pa-thai, Sreekanth, Gopinathan Pillai, Noisakran, Sansanee, Chu, Justin Jang Hann, Limjindaporn, Thawornchai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690425/
https://ncbi.nlm.nih.gov/pubmed/29145490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188121
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