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RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines
Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...
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| Publicat a: | PLoS One |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5690425/ https://ncbi.nlm.nih.gov/pubmed/29145490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188121 |
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