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RNAi screen reveals a role of SPHK2 in dengue virus–mediated apoptosis in hepatic cell lines

Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Morchang, Atthapan, Lee, Regina Ching Hua, Yenchitsomanus, Pa-thai, Sreekanth, Gopinathan Pillai, Noisakran, Sansanee, Chu, Justin Jang Hann, Limjindaporn, Thawornchai
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690425/
https://ncbi.nlm.nih.gov/pubmed/29145490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188121
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