Inhibition of p38MAPK and CD137 signaling reduce dengue virus-induced TNF-α secretion and apoptosis

BACKGROUND: Hepatic injury in dengue virus (DENV) infection is authenticated by hepatomegaly and an upsurge in transaminase levels. DENV replicates in hepatocytes and causes hepatocyte apoptosis both in vitro and in vivo. Understanding the molecular mechanisms of DENV-induced hepatic injury could fa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nagila, Amar, Netsawang, Janjuree, Suttitheptumrong, Aroonroong, Morchang, Atthapan, Khunchai, Sasiprapa, Srisawat, Chatchawan, Puttikhunt, Chunya, Noisakran, Sansanee, Yenchitsomanus, Pa-thai, Limjindaporn, Thawornchai
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2013
विषय:
Short Report
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639879/
https://ncbi.nlm.nih.gov/pubmed/23557259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-105
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