A Critical Regulatory Role for Macrophage Migration Inhibitory Factor in Hyperoxia-Induced Injury in the Developing Murine Lung

BACKGROUND: The role and mechanism of action of MIF in hyperoxia-induced acute lung injury (HALI) in the newborn lung are not known. We hypothesized that MIF is a critical regulatory molecule in HALI in the developing lung. METHODOLOGY: We studied newborn wild type (WT), MIF knockout (MIFKO), and MI...

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Hauptverfasser: Sun, Huanxing, Choo-Wing, Rayman, Sureshbabu, Angara, Fan, Juan, Leng, Lin, Yu, Shuang, Jiang, Dianhua, Noble, Paul, Homer, Robert J., Bucala, Richard, Bhandari, Vineet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639272/
https://ncbi.nlm.nih.gov/pubmed/23637753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060560
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