Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice

Administration of supplemental oxygen remains a critical clinical intervention for survival of preterm infants with respiratory failure. However, prolonged exposure to hyperoxia can augment pulmonary damage, resulting in developmental lung diseases embodied as hyperoxia-induced acute lung injury and...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Sureshbabu, Angara, Syed, Mansoor, Das, Pragnya, Janér, Cecilia, Pryhuber, Gloria, Rahman, Arshad, Andersson, Sture, Homer, Robert J., Bhandari, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105179/
https://ncbi.nlm.nih.gov/pubmed/27374190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0349OC
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