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Hyperoxia Exacerbates Postnatal Inflammation-Induced Lung Injury in Neonatal BRP-39 Null Mutant Mice Promoting the M1 Macrophage Phenotype

Rationale. Hyperoxia exposure to developing lungs—critical in the pathogenesis of bronchopulmonary dysplasia—may augment lung inflammation by inhibiting anti-inflammatory mediators in alveolar macrophages. Objective. We sought to determine the O(2)-induced effects on the polarization of macrophages...

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Detalhes bibliográficos
Main Authors: Syed, Mansoor A., Bhandari, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855965/
https://ncbi.nlm.nih.gov/pubmed/24347826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/457189
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