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Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia

BACKGROUND: The role and mechanism of action of MIF in bronchopulmonary dysplasia (BPD) are not known. We hypothesized that increased MIF signaling would ameliorate the pulmonary phenotype of BPD in the mouse lung. METHODS: We studied newborn wild type (WT), MIF knockout (MIFKO), and lung MIF transg...

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Detalhes bibliográficos
Main Authors: Sun, Huanxing, Choo-Wing, Rayman, Fan, Juan, Leng, Lin, Syed, Mansoor A, Hare, Alissa A, Jorgensen, William L, Bucala, Richard, Bhandari, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637059/
https://ncbi.nlm.nih.gov/pubmed/23448134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-27
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