Receptor agonists of macrophage migration inhibitory factor

The cytokine MIF is involved in inflammation and cell proliferation via pathways initiated by its binding to the transmembrane receptor CD74. MIF also promotes AMPK activation with potential benefits for response to myocardial infarction and ischaemia-reperfusion. Structure-based molecular design ha...

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Bibliografiska uppgifter
Huvudupphovsmän: Jorgensen, William L., Gandavadi, Sunilkumar, Du, Xin, Hare, Alissa A., Trofimov, Alexander, Leng, Lin, Bucala, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989669/
https://ncbi.nlm.nih.gov/pubmed/20971005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.09.118
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