Receptor agonists of macrophage migration inhibitory factor

The cytokine MIF is involved in inflammation and cell proliferation via pathways initiated by its binding to the transmembrane receptor CD74. MIF also promotes AMPK activation with potential benefits for response to myocardial infarction and ischaemia-reperfusion. Structure-based molecular design ha...

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Autors principals: Jorgensen, William L., Gandavadi, Sunilkumar, Du, Xin, Hare, Alissa A., Trofimov, Alexander, Leng, Lin, Bucala, Richard
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989669/
https://ncbi.nlm.nih.gov/pubmed/20971005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.09.118
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