Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver

BACKGROUND: Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver regeneration, and to identify their target mRNAs. RESULTS: miRNA recruitment to the RISC is highly dynamic, changing more than five-fold f...

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Main Authors: Schug, Jonathan, McKenna, Lindsay B, Walton, Gabriel, Hand, Nicholas, Mukherjee, Sarmistha, Essuman, Kow, Shi, Zhongjie, Gao, Yan, Markley, Karen, Nakagawa, Momo, Kameswaran, Vasumathi, Vourekas, Anastassios, Friedman, Joshua R, Kaestner, Klaus H, Greenbaum, Linda E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639193/
https://ncbi.nlm.nih.gov/pubmed/23597149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-264
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