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The diabetes gene Hhex maintains δ-cell differentiation and islet function
The homeodomain transcription factor HHEX (hematopoietically expressed homeobox) has been repeatedly linked to type 2 diabetes mellitus (T2DM) using genome-wide association studies. We report here that within the adult endocrine pancreas, Hhex is selectively expressed in the somatostatin-secreting δ...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003275/ https://ncbi.nlm.nih.gov/pubmed/24736842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.235499.113 |
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