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B7-H1 Promotes Germinal Center B cell Survival and Inhibits T cell Activation
The immune system has developed several regulatory mechanisms to maintain homeostasis of adaptive immune responses. T cell PD-1 recognition of B7-H1 (PD-L1) expressed on antigen presenting cells and non-lymphoid tissue regulates T cell activation. We show that B7-H1(−/−) mice exhibit exacerbated pro...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638795/ https://ncbi.nlm.nih.gov/pubmed/21061440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040690 |
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